Preimplantation Genetic Analysis

GeneTech's pre implantation genetic analysis gives information about embryos’ genetic health to help infertility specialists select the best embryo for transfer and improve chances of achieving a successful pregnancy. It is planned usually for couples with recurrent pregnancy losses, recurrent IVF failures and with family history of any inherited monogenic disorder.

 

S.No Test name TAT (Days)
1 PGT-A (PGS) for Aneuploidies 15
2 PGT-M (PGD) for Monogenic/Mendelian Disorders 15

Sample Collection:
Embryo Biopsy in media and collection box supplied by GeneTech
Transport within 48 hrs at 2-8 degrees centigrade.

Preimplantation genetic testing for aneuploidy or PGT-A (formerly PGS)

  • Routinely used for all IVF conceptions
  • 3rd or 5th day embryo biopsy
  • Identifies aneuploidies in embryo(s)
  • NGS based Whole genome amplification and sequencing
  • Increases success rate of IVF
  • Higher chance of pregnancy
  • Reduced risk of miscarriage
  • Reduced number of IVF cycles
  • Saves time and cost

Preimplantation genetic testing for Mongenic disorders or PGT-M (formerly PGD)

  • Used in cases where the parents are identified carriers for a single-gene (or monogenic) disorder like Thalassemia, DMD, Fragile-X
  • Also used in HLA matching
  • 3rd day or 5th day embryo biopsy is used to determine existence of single-gene mutation in homozygous or heterozygous condition
  • NGS, Sanger and PCR based
  • Our PGT-M portfolio is constantly upgraded with new genetic disorders. Call for details.