Indications for Reproductive Genetics

Indications For Reproductive Genetics

Genes influence reproductive health starting from the formation of gamete to delivery of full-term fetus by regulating implantation, embryonic development, and child birth. The following are some of the important and broad categories of indications which need genetic testing.

Premature Ovarian Failure/Insufficiency

Primary Amennorhea, Secondary Amennorhea


 Idiopathic, Obesity Related, Endometriosis

ART Failure

Recurrent Failure of Assisted Reproductive Methods  (IVF, ICSI, IUI)

Poly Cystic Ovarian Syndrome (PCOS)

 Irregular Periods, Hormonal, Hereditary

Sperm Defects

Azoospermia, Oligospermia, Teratozoospermia, Asthenospermia

Pregnancy Loss

 Recurrent, Missed, Spontaneous abortions

Ultrasound Fetal Malformations

Anencephaly, NT, Cystic Hygroma Spina Bifida, Oligohydramnios, Skeletal Dysplasias

Pregnancy Complications

 Pre-eclampsia, Gestational Diabetes

Positive Family History

History of inherited genetic disorder in previous child or fetus/parent or family member


First/Second cousins, maternal niece marriage, known carrier parent for recessive disorders

Familial Breast or Ovarian Cancer

 Breast, Ovarian, Prostate and Colon Cancer Predisposition