Chapter on Femilial Cancer Genetics in the book Oncofertility-clinical Practice and Implementation Challenges (2025).

The chapter demonstrates that hereditary cancer syndromes are a diverse group of genetic disorders associated with significantly increased risk for tumor development due to the presence of germline mutations. It specifically describes genetic basis of cancer susceptibility syndromes, their inheritance, and available reproductive options for couple planning to conceive through prenatal diagnosis or embryo testing. Salient points of genetic counseling and its crucial role in disseminating information to couples and enabling informed decision making regarding reproductive choices are covered. The chapter also touches upon the complexities of genetic inheritance, ethical dilemmas and guidelines of professional bodies on risk detection, fertility preservation and pre-implantation genetic testing.